Abstract Background Epithelial mesenchymal transition (EMT) massager-standard is tightly regulated by a network of transcription factors (EMT-TFs).Among them is the nuclear factor ZEB2, a member of the zinc-finger E-box binding homeobox family.ZEB2 nuclear localization has been identified in several cancer types, and its overexpression is correlate
Extant enzymes are not only highly efficient biocatalysts for a single, or a group of chemically closely related substrates but often have retained, as a mark of their evolutionary history, a certain degree of substrate ambiguity.We have exploited the substrate ambiguity of the ectoine hydroxylase (EctD), a member of the non-heme Fe(II)-containing
In the matter of Le Sueur v Ethekwini Municipality the KwaZulu-Natal High Court decided that municipalities Beanies had the power to legislate on environmental issues such as biodiversity and conservation.This note argues that the precedent established in this case is that municipalities have authority to legislate upon environmental matters as an
Focused ultrasound (FUS) is a rapidly developing stimulus technology with the potential to uncover novel mechanosensory dependent cellular processes.Since it is non-invasive, it holds great promise for future therapeutic applications in patients used either alone or as a complement to boost existing treatments.For example, FUS stimulation causes in